Brucella abortus Induces the Secretion of Proinflammatory Mediators from Glial Cells Leading to Astrocyte Apoptosis

Central nervous system (CNS) invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. In this study we present in vivo and in vitro evidence that B. abortus and its lipoproteins activate the innate immunity of the CNS, eliciting an inflammatory response...

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Detalhes bibliográficos
Main Authors: García Samartino, Clara, Delpino, M. Victoria, Pott Godoy, Clara, Di Genaro, María Silvia, Pasquevich, Karina A., Zwerdling, Astrid, Barrionuevo, Paula, Mathieu, Patricia, Cassataro, Juliana, Pitossi, Fernando, Giambartolomei, Guillermo H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830821/
https://ncbi.nlm.nih.gov/pubmed/20093491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090503
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