Brucella abortus Induces the Secretion of Proinflammatory Mediators from Glial Cells Leading to Astrocyte Apoptosis

Central nervous system (CNS) invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. In this study we present in vivo and in vitro evidence that B. abortus and its lipoproteins activate the innate immunity of the CNS, eliciting an inflammatory response...

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Main Authors: García Samartino, Clara, Delpino, M. Victoria, Pott Godoy, Clara, Di Genaro, María Silvia, Pasquevich, Karina A., Zwerdling, Astrid, Barrionuevo, Paula, Mathieu, Patricia, Cassataro, Juliana, Pitossi, Fernando, Giambartolomei, Guillermo H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2010
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830821/
https://ncbi.nlm.nih.gov/pubmed/20093491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090503
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