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Role of Efflux Pumps and Intracellular Thiols in Natural Antimony Resistant Isolates of Leishmania donovani

BACKGROUND: In view of the recent upsurge in the phenomenon of therapeutic failure, drug resistance in Leishmania , developed under natural field conditions, has become a great concern yet little understood. Accordingly, the study of determinants of antimony resistance is urgently warranted. Efflux...

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Bibliographic Details
Main Authors: Rai, Smita, Bhaskar, Goel, Sudhir K., Nath Dwivedi, Upendra, Sundar, Shyam, Goyal, Neena
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775726/
https://ncbi.nlm.nih.gov/pubmed/24069359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074862
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