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Randomized Trial of Zileuton for Treatment of COPD Exacerbations Requiring Hospitalization
RATIONALE: Leukotrienes have been implicated in the pathogenesis of acute exacerbations of COPD, but leukotriene modifiers have not been studied as a possible therapy for exacerbations. OBJECTIVE: We sought to test the safety and efficacy of adding oral zileuton (a 5-lipoxygenase inhibitor) to usual...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775706/ https://ncbi.nlm.nih.gov/pubmed/21299475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/15412555.2010.540273 |
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