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Testing for Non-Random Mating: Evidence for Ancestry-Related Assortative Mating in the Framingham Heart Study

Population stratification leads to a predictable phenomenon—a reduction in the number of heterozygotes compared to that calculated assuming Hardy-Weinberg Equilibrium (HWE). We show that population stratification results in another phenomenon—an excess in the proportion of spouse-pairs with the same...

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Detalhes bibliográficos
Main Authors: Sebro, Ronnie, Hoffman, Thomas J., Lange, Christoph, Rogus, John J., Risch, Neil J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775670/
https://ncbi.nlm.nih.gov/pubmed/20842694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20528
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