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Synthesis of the Tolerance-Inducing Oligosaccharide Lacto-N-Fucopentaose III Bearing an Activated Linker

A concise synthetic route to an immunomodulatory pentasaccharide, lacto-N-fucopentaose III (1) and its corresponding human serum albumin conjugate, is described. Key transformations of the strategy include two highly regio- and stereoselective glycosylations for the construction of disaccharide 10 a...

詳細記述

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書誌詳細
主要な著者: Zhang, Junfeng, Zou, Lu, Lowary, Todd L
フォーマット: Artigo
言語:Inglês
出版事項: WILEY-VCH Verlag 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775522/
https://ncbi.nlm.nih.gov/pubmed/24551556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201300024
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