Synthesis of the Tolerance-Inducing Oligosaccharide Lacto-N-Fucopentaose III Bearing an Activated Linker

A concise synthetic route to an immunomodulatory pentasaccharide, lacto-N-fucopentaose III (1) and its corresponding human serum albumin conjugate, is described. Key transformations of the strategy include two highly regio- and stereoselective glycosylations for the construction of disaccharide 10 a...

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Hlavní autoři: Zhang, Junfeng, Zou, Lu, Lowary, Todd L
Médium: Artigo
Jazyk:Inglês
Vydáno: WILEY-VCH Verlag 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775522/
https://ncbi.nlm.nih.gov/pubmed/24551556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201300024
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