Immunomodulatory Glycan Lacto-N-Fucopentaose III Requires Clathrin-Mediated Endocytosis To Induce Alternative Activation of Antigen-Presenting Cells

The mechanism of alternative activation of antigen-presenting cells (APCs) is largely unknown. Lacto-N-fucopentaose III (LNFPIII) is a biologically conserved pentasaccharide that contains the Lewis(x) trisaccharide. LNFPIII conjugates and schistosome egg antigens, which contain the Lewis(x) trisacch...

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Hlavní autoři: Srivastava, Leena, Tundup, Smanla, Choi, Beak-San, Norberg, Thomas, Harn, Donald
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993454/
https://ncbi.nlm.nih.gov/pubmed/24566617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01293-13
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