Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation

Psoriasis is an inflammatory cutaneous disorder characterized by marked epidermal thickening and Th1 and Th17 cell infiltration. At present, the contribution of B cells to the pathogenesis of psoriasis is unclear. In mice, topical application of imiquimod induces inflamed skin lesions and serves as...

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Bibliographic Details
Main Authors: Yanaba, Koichi, Kamata, Masahiro, Ishiura, Nobuko, Shibata, Sayaka, Asano, Yoshihide, Tada, Yayoi, Sugaya, Makoto, Kadono, Takafumi, Tedder, Thomas F., Sato, Shinichi
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2013
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Spotlight on Leading Edge Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774845/
https://ncbi.nlm.nih.gov/pubmed/23630391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1112562
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