Nucleotide receptor P2RX(7) stimulation enhances LPS-induced interferon-β production in murine macrophages

Stimulation of P2RX(7) with extracellular ATP potentiates numerous LPS-induced proinflammatory events, including cytokine induction in macrophages, but the molecular mechanisms underlying this process are not well defined. Although P2RX(7) ligation has been proposed to activate several transcription...

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Bibliographic Details
Main Authors: Gavala, M. L., Liu, Y.-P., Lenertz, L. Y., Zeng, L., Blanchette, J. B., Guadarrama, A. G., Denlinger, L. C., Bertics, P. J., Smith, J. A.
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2013
Subjects:
Receptors, Signal Transduction, & Genes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774844/
https://ncbi.nlm.nih.gov/pubmed/23911869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0712351
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