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Activation of the Transcription Factor FosB/Activating Protein-1 (AP-1) Is a Prominent Downstream Signal of the Extracellular Nucleotide Receptor P2RX7 in Monocytic and Osteoblastic Cells

Activation of the ionotropic P2RX7 nucleotide receptor by extracellular ATP has been implicated in modulating inflammatory disease progression. Continuous exposure of P2RX7 to ligand can result in apoptosis in many cell types, including monocytic cells, whereas transient activation of P2RX7 is linke...

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Bibliografski detalji
Glavni autori: Gavala, Monica L., Hill, Lindsay M., Lenertz, Lisa Y., Karta, Maya R., Bertics, Paul J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962527/
https://ncbi.nlm.nih.gov/pubmed/20813842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142091
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