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Cyclin-dependent kinase inhibitor Cdkn2c regulates B cell homeostasis and function in the NZM2410-derived murine lupus susceptibility locus Sle2c1

Sle2c1 is an NZM2410 and NZB-derived lupus susceptibility locus that induces an expansion of the B1a cell compartment. B1a cells have a repertoire enriched for autoreactivity, and an expansion of this B cell subset occurs in several mouse models of lupus. A combination of genetic mapping and candida...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Xu, Zhiwei, Potula, Hari-Hara SK, Vallurupalli, Anusha, Perry, Daniel, Baker, Henry, Croker, Byron P., Dozmorov, Igor, Morel, Laurence
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774832/
https://ncbi.nlm.nih.gov/pubmed/21543644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002544
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