The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin

Prolonged fasting is associated with a downregulation of the hypothalamo-pituitary thyroid (H-P-T) axis, which is reversed by administration of leptin. The hypothalamic melanocortin system regulates energy balance and mediates a number of central effects of leptin. In this study, we show that hypoth...

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Main Authors: Kim, M.S., Small, C.J., Stanley, S.A, Morgan, D.G.A., Seal, L.J., Kong, W.M., Edwards, C.M.B., Abusnana, S., Sunter, D., Ghatei, M.A., Bloom, S.R.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC377483/
https://ncbi.nlm.nih.gov/pubmed/10749579
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