Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein

Human coronavirus OC43 (HCoV-OC43) is a causative agent of the common cold. The nucleocapsid (N) protein, which is a major structural protein of CoVs, binds to the viral RNA genome to form the virion core and results in the formation of the ribonucleoprotein (RNP) complex. We have solved the crystal...

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Main Authors: Chen, I.-Jung, Yuann, Jeu-Ming P., Chang, Yu-Ming, Lin, Shing-Yen, Zhao, Jincun, Perlman, Stanley, Shen, Yo-Yu, Huang, Tai-Huang, Hou, Ming-Hon
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier B.V. 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774783/
https://ncbi.nlm.nih.gov/pubmed/23501675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2013.03.003
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