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Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein

Human coronavirus OC43 (HCoV-OC43) is a causative agent of the common cold. The nucleocapsid (N) protein, which is a major structural protein of CoVs, binds to the viral RNA genome to form the virion core and results in the formation of the ribonucleoprotein (RNP) complex. We have solved the crystal...

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Bibliografiske detaljer
Main Authors: Chen, I.-Jung, Yuann, Jeu-Ming P., Chang, Yu-Ming, Lin, Shing-Yen, Zhao, Jincun, Perlman, Stanley, Shen, Yo-Yu, Huang, Tai-Huang, Hou, Ming-Hon
Format: Artigo
Sprog:Inglês
Udgivet: Published by Elsevier B.V. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774783/
https://ncbi.nlm.nih.gov/pubmed/23501675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2013.03.003
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