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Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1

The ras family of small GTP-binding proteins exerts powerful effects upon cell structure and function. One member of this family, rac, induces actin cytoskeletal reorganization in nonmuscle cells and hypertrophic changes in cultured cardiomyocytes. To examine the effect of rac1 activation upon cardi...

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Detalhes bibliográficos
Main Authors: Sussman, Mark A., Welch, Sara, Walker, Angela, Klevitsky, Raisa, Hewett, Timothy E., Price, Robert L., Schaefer, Erik, Yager, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC377478/
https://ncbi.nlm.nih.gov/pubmed/10749567
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