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Impact of Toll-Like Receptor 2 Deficiency on Survival and Neurological Function after Cardiac Arrest: A Murine Model of Cardiopulmonary Resuscitation

BACKGROUND: Cardiac arrest (CA) followed by cardiopulmonary resuscitation (CPR) is associated with poor survival rate and neurofunctional outcome. Toll-like receptor 2 (TLR2) plays an important role in conditions of sterile inflammation such as reperfusion injury. Recent data demonstrated beneficial...

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Detalhes bibliográficos
Main Authors: Bergt, Stefan, Güter, Anne, Grub, Andrea, Wagner, Nana-Maria, Beltschany, Claudia, Langner, Sönke, Wree, Andreas, Hildebrandt, Steve, Nöldge-Schomburg, Gabriele, Vollmar, Brigitte, Roesner, Jan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774715/
https://ncbi.nlm.nih.gov/pubmed/24066159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074944
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