Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes

We have recently shown that a single injection of mature, antigen-pulsed, human dendritic cells (DCs) rapidly elicits CD4(+) and CD8(+) T-cell immunity in vivo. The DCs were pulsed with 2 foreign proteins, keyhole limpet hemocyanin (KLH) and tetanus toxoid (TT), as well as an HLA A2.1-restricted inf...

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Bibliographic Details
Main Authors: Dhodapkar, Madhav V., Krasovsky, Joseph, Steinman, Ralph M., Bhardwaj, Nina
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
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Rapid Publication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC377466/
https://ncbi.nlm.nih.gov/pubmed/10727452
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