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Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4

Atopic individuals are predisposed to mounting vigorous Th2-type immune responses to environmental allergens. To determine the factors responsible, animal models that closely mimic natural modes of allergen exposure should prove most informative. Therefore, we investigated the role of IL-4, a known...

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Autori principali: Herrick, Christina A., MacLeod, Heather, Glusac, Earl, Tigelaar, Robert E., Bottomly, Kim
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC377464/
https://ncbi.nlm.nih.gov/pubmed/10727445
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