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Immunodeficiency due to defects in store-operated calcium entry
Mutations in genes encoding the Calcium-Release Activated Calcium (CRAC) channel abolish calcium influx in cells of the immune system and cause severe congenital immunodeficiency. Patients with autosomal recessive mutations in the CRAC channel gene ORAI1, its activator Stromal Interaction Molecule 1...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774594/ https://ncbi.nlm.nih.gov/pubmed/22129055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2011.06240.x |
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