Role of genetic modifiers in an orthologous rat model of ARPKD

Human data and animal models of autosomal recessive polycystic kidney disease (ARPKD) suggest that genetic factors modulate the onset and severity of the disease. We report here for the first time that ARPKD susceptibility is attenuated by introgressing the mutated Pkhd1 disease allele from the poly...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: O'Meara, Caitlin C., Hoffman, Matthew, Sweeney, William E., Tsaih, Shirng-Wern, Xiao, Bing, Jacob, Howard J., Avner, Ellis D., Moreno, Carol
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774585/
https://ncbi.nlm.nih.gov/pubmed/22669842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00187.2011
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars