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Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves’ disease

We performed genetic immunization of outbred NMRI mice, using a cDNA encoding the human thyrotropin receptor (TSHr). All mice produced antibodies capable of recognizing the recombinant receptor expressed at the surface of stably transfected Chinese hamster ovary (CHO) cells, and sera from most of th...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Costagliola, Sabine, Many, Marie-Christine, Denef, Jean-François, Pohlenz, Joachim, Refetoff, Samuel, Vassart, Gilbert
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC377458/
https://ncbi.nlm.nih.gov/pubmed/10727449
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