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Alignment of sarcoplasmic reticulum-mitochondrial junctions with mitochondrial contact points

Propagation of ryanodine receptor (RyR2)-derived Ca(2+) signals to the mitochondrial matrix supports oxidative ATP production or facilitates mitochondrial apoptosis in cardiac muscle. Ca(2+) transfer likely occurs locally at focal associations of the sarcoplasmic reticulum (SR) and mitochondria, whi...

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Autors principals: García-Pérez, Cecília, Schneider, Timothy G., Hajnóczky, György, Csordás, György
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774555/
https://ncbi.nlm.nih.gov/pubmed/21856920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00397.2011
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