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Physical Coupling Supports the Local Ca(2+) Transfer between Sarcoplasmic Reticulum Subdomains and the Mitochondria in Heart Muscle

In many cell types, transfer of Ca(2+) released via ryanodine receptors (RyR) to the mitochondrial matrix is locally supported by high [Ca(2+)] microdomains at close contacts between the sarcoplasmic reticulum (SR) and mitochondria. Here we studied whether the close contacts were secured via direct...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: García-Pérez, Cecilia, Hajnóczky, György, Csordás, György
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395082/
https://ncbi.nlm.nih.gov/pubmed/18790739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803385200
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