Tumor-infiltrating regulatory T cells inhibit endogenous cytotoxic T cell responses to lung adenocarcinoma

Immune cells comprise a substantial proportion of the tumor mass in human non-small cell lung cancers (NSCLC), but the precise composition and significance of this infiltration is unclear. Herein we examined immune complexity of human NSCLC as well as NSCLC developing in CC10-TAg transgenic mice, an...

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Bibliographic Details
Main Authors: Ganesan, Anusha-Preethi, Johansson, Magnus, Ruffell, Brian, Beltran, Adam, Lau, Jonathan, Jablons, David M., Coussens, Lisa M.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774528/
https://ncbi.nlm.nih.gov/pubmed/23851682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301317
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