Pancreatic Ductal Adenocarcinoma Contains an Effector and Regulatory Immune Cell Infiltrate that Is Altered by Multimodal Neoadjuvant Treatment

OBJECTIVE: The immune response to pancreatic ductal adenocarcinoma (PDA) may play a role in defining its uniquely aggressive biology; therefore, we sought to clearly define the adaptive immune infiltrate in PDA. DESIGN: We used immunohistochemistry and flow cytometry to characterize the immune infil...

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Hauptverfasser: Shibuya, Kendall C., Goel, Vikas K., Xiong, Wei, Sham, Jonathan G., Pollack, Seth M., Leahy, Allison M., Whiting, Samuel H., Yeh, Matthew M., Yee, Cassian, Riddell, Stanley R., Pillarisetty, Venu G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008589/
https://ncbi.nlm.nih.gov/pubmed/24794217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096565
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