Blunted IgE-mediated activation of mast cells in mice lacking the serum- and glucocorticoid-inducible kinase SGK3

Previous studies have shown that pharmacological inhibition of the phosphoinositol-3 (PI3) kinase disrupts the activation of mast cells. Through phosphoinositide-dependent kinase PDK1, PI3 kinase activates the serum- and glucocorticoid-inducible kinase 3 (SGK3). The present study explored the role o...

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Main Authors: Zemtsova, Irina M., Heise, Nicole, Fröhlich, Henning, Qadri, Syed M., Kucherenko, Yuliya, Boini, Krishna M., Pearce, David, Shumilina, Ekaterina, Lang, Florian
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2010
Teme:
Receptors and Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774517/
https://ncbi.nlm.nih.gov/pubmed/20686074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00539.2009
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