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Central nociceptin/orphanin FQ system elevates food consumption by both increasing energy intake and reducing aversive responsiveness

Nociceptin/orphanin FQ (N/OFQ), the nociceptin opioid peptide (NOP) receptor ligand, increases feeding when injected centrally. Initial data suggest that N/OFQ blocks the development of a conditioned taste aversion (CTA). The current project further characterized the involvement of N/OFQ in the regu...

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Autors principals: Olszewski, Pawel K., Grace, Martha K., Fard, Shahrzad Shirazi, Le Grevès, Madeleine, Klockars, Anica, Massi, Maurizio, Schiöth, Helgi B., Levine, Allen S.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774471/
https://ncbi.nlm.nih.gov/pubmed/20427724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00556.2009
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