Differential Role of PTEN Phosphatase in Chemotactic Growth Cone Guidance

Negatively targeting the tumor suppressor and phosphoinositide phosphatase PTEN (phosphatase and tensin homologue) promotes axon regrowth after injury. How PTEN functions in axon guidance has remained unknown. Here we report the differential role of PTEN in chemotactic guidance of axonal growth cone...

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Bibliographic Details
Main Authors: Henle, Steven J., Carlstrom, Lucas P., Cheever, Thomas R., Henley, John R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
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Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774355/
https://ncbi.nlm.nih.gov/pubmed/23775074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.487066
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