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Amyloid Precursor Protein Is an Autonomous Growth Cone Adhesion Molecule Engaged in Contact Guidance

Amyloid precursor protein (APP), a transmembrane glycoprotein, is well known for its involvement in the pathogenesis of Alzheimer disease of the aging brain, but its normal function is unclear. APP is a prominent component of the adult as well as the developing brain. It is enriched in axonal growth...

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Detalhes bibliográficos
Main Authors: Sosa, Lucas J., Bergman, Jared, Estrada-Bernal, Adriana, Glorioso, Thomas J., Kittelson, John M., Pfenninger, Karl H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653867/
https://ncbi.nlm.nih.gov/pubmed/23691241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064521
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