Effects of high-fat diet feeding on Znt8-null mice: differences between β-cell and global knockout of Znt8

Genomewide association studies have linked a polymorphism in the zinc transporter 8 (Znt8) gene to higher risk of developing type 2 diabetes. Znt8 is highly expressed in pancreatic β-cells where it is involved in the regulation of zinc transport into granules. However, Znt8 is also expressed in othe...

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Hlavní autoři: Hardy, A. B., Wijesekara, N., Genkin, I., Prentice, K. J., Bhattacharjee, A., Kong, D., Chimienti, F., Wheeler, M. B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774340/
https://ncbi.nlm.nih.gov/pubmed/22338079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00448.2011
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