Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-κB

Radiation therapy is an essential modality in the treatment of colorectal cancers. Radiation exerts an antiangiogenic effect on tumors, inhibiting endothelial proliferation and survival in the tumor microvasculature. However, damage from low levels of irradiation can induce a paradoxical effect, sti...

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Autores principales: Rafiee, Parvaneh, Binion, David G., Wellner, Michael, Behmaram, Behnaz, Floer, Martin, Mitton, Elizabeth, Nie, Linghui, Zhang, Zhihong, Otterson, Mary F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2010
Materias:
Inflammation/Immunity/Mediators
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774333/
https://ncbi.nlm.nih.gov/pubmed/20299603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00339.2009
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