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Matrix metalloproteinase-7–dependent release of tumor necrosis factor-α in a model of herniated disc resorption

Herniated disc (HD), one of the major causes of low back pain, is often resolved spontaneously without surgical intervention. Resorption is associated with a marked increase in infiltrating macrophages, and the matrix metalloproteinases (MMP) MMP-3 and MMP-7 have been implicated in this phenomenon....

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Detalhes bibliográficos
Main Authors: Haro, Hirotaka, Crawford, Howard C., Fingleton, Barbara, Shinomiya, Kenichi, Spengler, Dan M., Matrisian, Lynn M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC377426/
https://ncbi.nlm.nih.gov/pubmed/10642592
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