Matrix metalloproteinase-3–dependent generation of a macrophage chemoattractant in a model of herniated disc resorption

Herniated disc (HD) is a common health problem that is resolved by surgery unless spontaneous resorption occurs. HD tissue contains abundant macrophage infiltration and high levels of matrix metalloproteinases (MMPs) MMP-3 and MMP-7. We developed a model system in which disc tissue or isolated chond...

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Autors principals: Haro, Hirotaka, Crawford, Howard C., Fingleton, Barbara, MacDougall, John R., Shinomiya, Kenichi, Spengler, Dan M., Matrisian, Lynn M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2000
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC377425/
https://ncbi.nlm.nih.gov/pubmed/10642591
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