Ryanodine receptors contribute to bile acid-induced pathological calcium signaling and pancreatitis in mice

Biliary pancreatitis is the most common etiology for acute pancreatitis, yet its pathophysiological mechanism remains unclear. Ca(2+) signals generated within the pancreatic acinar cell initiate the early phase of pancreatitis, and bile acids can elicit anomalous acinar cell intracellular Ca(2+) rel...

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Detalhes bibliográficos
Main Authors: Husain, Sohail Z., Orabi, Abrahim I., Muili, Kamaldeen A., Luo, Yuhuan, Sarwar, Sheharyar, Mahmood, Syeda Maham, Wang, Dong, Choo-Wing, Rayman, Singh, Vijay P., Parness, Jerome, Ananthanaravanan, Meena, Bhandari, Vineet, Perides, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Pancreas
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774209/
https://ncbi.nlm.nih.gov/pubmed/22517774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00546.2011
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