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Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation
Stromal derived follicular dendritic cells (FDCs) are a major reservoir for antigen that is essential for formation of germinal centers, the site where memory and effector B cells differentiate. A long-standing question is how FDCs retain antigen in its native form for extended periods and how they...
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Main Authors: | , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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2013
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773956/ https://ncbi.nlm.nih.gov/pubmed/23770227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.02.023 |
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