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Diclofenac enables unprecedented week-long microneedle-enhanced delivery of a skin impermeable medication in humans
Microneedles applied to the skin create micropores, allowing transdermal drug delivery of skin-impermeable compounds. The first human study with this technique demonstrated delivery of naltrexone (an opioid antagonist) for two to three days. Rapid micropore closure, however, blunts the delivery wind...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773937/ https://ncbi.nlm.nih.gov/pubmed/23761054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1036-1 |
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