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Diclofenac enables unprecedented week-long microneedle-enhanced delivery of a skin impermeable medication in humans

Microneedles applied to the skin create micropores, allowing transdermal drug delivery of skin-impermeable compounds. The first human study with this technique demonstrated delivery of naltrexone (an opioid antagonist) for two to three days. Rapid micropore closure, however, blunts the delivery wind...

詳細記述

保存先:
書誌詳細
主要な著者: Brogden, Nicole K., Banks, Stan L., Crofford, Leslie J., Stinchcomb, Audra L.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773937/
https://ncbi.nlm.nih.gov/pubmed/23761054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1036-1
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