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Parathyroid hormone-related protein regulates integrin α6 and β4 levels via transcriptional and post-translational pathways

Parathyroid hormone-related protein (PTHrP) enhances prostate cancer (CaP) growth and metastasis in vivo. PTHrP also increases cell survival and migration, and upregulates pro-invasive integrin α6β4 expression. We used the human CaP cell lines C4-2 and PC-3 as model systems to study the mechanisms v...

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Detalhes bibliográficos
Main Authors: Bhatia, Vandanajay, Mula, Ramanjaneya V.R., Falzon, Miriam
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773845/
https://ncbi.nlm.nih.gov/pubmed/23499737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2013.03.003
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