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Parathyroid Hormone-related Protein Regulates Cell Survival Pathways via Integrin α6β4-mediated Activation of PI3-K/Akt Signaling
Parathyroid hormone-related protein (PTHrP) is expressed by human prostatic tissues and cancer cell lines. PTHrP enhances tumor cell growth and metastasis in vivo and upregulates pro-invasive integrin α6β4 expression in vitro. Hallmarks of malignant tumor cells include resistance to apoptosis and an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755566/ https://ncbi.nlm.nih.gov/pubmed/19584267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0568 |
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