Role of the circadian clock gene Per2 in adaptation to cold temperature

Adaptive thermogenesis allows mammals to resist to cold. For instance, in brown adipose tissue (BAT) the facultative uncoupling of the proton gradient from ATP synthesis in mitochondria is used to generate systemic heat. However, this system necessitates an increase of the Uncoupling protein 1 (Ucp1...

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Detalhes bibliográficos
Main Authors: Chappuis, Sylvie, Ripperger, Jürgen Alexander, Schnell, Anna, Rando, Gianpaolo, Jud, Corinne, Wahli, Walter, Albrecht, Urs
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773826/
https://ncbi.nlm.nih.gov/pubmed/24049733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.05.002
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