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Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation

Hereditary spastic paraplegias are inherited neurological disorders characterized by progressive lower-limb spasticity and weakness. Although more than 50 genetic loci are known [spastic gait (SPG)1 to -57], over half of hereditary spastic paraplegia cases are caused by pathogenic mutations in four...

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Autors principals: Chang, Jaerak, Lee, Seongju, Blackstone, Craig
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773775/
https://ncbi.nlm.nih.gov/pubmed/23969831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307391110
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