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Protrudin Regulates Endoplasmic Reticulum Morphology and Function Associated with the Pathogenesis of Hereditary Spastic Paraplegia

Protrudin is a membrane protein that regulates polarized vesicular trafficking in neurons. The protrudin gene (ZFYVE27) is mutated in a subset of individuals with hereditary spastic paraplegia (HSP), and protrudin is therefore also referred to as spastic paraplegia (SPG) 33. We have now generated mi...

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Detalles Bibliográficos
Main Authors: Hashimoto, Yutaka, Shirane, Michiko, Matsuzaki, Fumiko, Saita, Shotaro, Ohnishi, Takafumi, Nakayama, Keiichi I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036311/
https://ncbi.nlm.nih.gov/pubmed/24668814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.528687
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