Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms

Aggressive cancers often express E-cadherin in cytoplasmic vesicles rather than on the plasma membrane and this may contribute to the invasive phenotype of these tumors. Therapeutic strategies are not currently available that restore the anti-invasive function of E-cadherin in cancers. MDA-MB-231 ce...

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Hlavní autoři: Law, ME, Corsino, PE, Jahn, SC, Davis, BJ, Chen, S, Patel, B, Pham, K, Lu, J, Sheppard, B, Nørgaard, P, Hong, J, Higgins, P, Kim, J-S, Luesch, H, Law, BK
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773700/
https://ncbi.nlm.nih.gov/pubmed/22543582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.138
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