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Differential Effect of Orexin-1 and CRF-1 Antagonism on Stress Circuits: a fMRI Study in the Rat with the Pharmacological Stressor Yohimbine

Translational approaches to study the neural substrates of stress and assess the mechanistic efficacy of novel anti-anxiety agents necessitate the use of stressors with a similar degree of saliency across species. The alpha-2 adrenoreceptor antagonist yohimbine represents an attractive experimental...

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Detalhes bibliográficos
Main Authors: Gozzi, Alessandro, Lepore, Stefano, Vicentini, Elena, Merlo-Pich, Emilio, Bifone, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773661/
https://ncbi.nlm.nih.gov/pubmed/23736277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.109
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