Renal Nitric Oxide Synthase and Antioxidant Preservation in Cyp1a1-Ren-2 Transgenic Rats With Inducible Malignant Hypertension

BACKGROUND: Dietary administration of 0.30% indole-3-carbinol (I3C) to Cyp1a1-Ren2 transgenic rats (TGRs) generates angiotensin II (ANG II)–dependent malignant hypertension (HTN) and increased renal vascular resistance. However, TGRs with HTN maintain a normal or slightly reduced glomerular filtrati...

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Bibliografiske detaljer
Main Authors: Cunningham, Mark W., Sasser, Jennifer M., West, Crystal A., Milani, Carlo J., Baylis, Chris, Mitchell, Kenneth D.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773572/
https://ncbi.nlm.nih.gov/pubmed/23764378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpt096
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