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Biomimetic Antigenic Nanoparticles Elicit Controlled Protective Immune Response to Influenza

Here we present a biomimetic strategy towards nanoparticle design for controlled immune response through encapsulation of conserved internal influenza proteins on the interior of virus like particles (VLPs) to direct CD8(+) cytotoxic T cell protection. Programmed encapsulation and sequestration of t...

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Detalhes bibliográficos
Main Authors: Patterson, Dustin P., Rynda-Apple, Agnieszka, Harmsen, Ann L., Harmsen, Allen G., Douglas, Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773536/
https://ncbi.nlm.nih.gov/pubmed/23540530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn4006544
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