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Biomimetic Antigenic Nanoparticles Elicit Controlled Protective Immune Response to Influenza

Here we present a biomimetic strategy towards nanoparticle design for controlled immune response through encapsulation of conserved internal influenza proteins on the interior of virus like particles (VLPs) to direct CD8(+) cytotoxic T cell protection. Programmed encapsulation and sequestration of t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Patterson, Dustin P., Rynda-Apple, Agnieszka, Harmsen, Ann L., Harmsen, Allen G., Douglas, Trevor
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773536/
https://ncbi.nlm.nih.gov/pubmed/23540530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn4006544
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