Poly ADP-Ribose Polymerase Inhibition Ameliorates Hind Limb Ischemia Reperfusion Injury in a Murine Model of Type 2 Diabetes

INTRODUCTION: Diabetes is known to increase poly-ADP-ribose-polymerase (PARP) activity and posttranslational poly-ADP-ribosylation of several regulatory proteins involved in inflammation and energy metabolism. These experiments test the hypothesis that PARP inhibition will modulate hind limb ischemi...

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Detaylı Bibliyografya
Asıl Yazarlar: Long, Chandler A., Boloum, Valy, Albadawi, Hassan, Tsai, Shirling, Yoo, Hyung-Jin, Oklu, Rahmi, Goldman, Mitchell H., Watkins, Michael T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773522/
https://ncbi.nlm.nih.gov/pubmed/23549425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0b013e31828cced3
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