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Hbo1 is a cyclin E/CDK2 substrate that enriches for breast cancer stem-like cells

Expression of cyclin E proteolytic cleavage products, low molecular weight cyclin E (LMW-E), is associated with poor clinical outcome in breast cancer patients and enhances tumorigenecity in mouse models. Here, we report that LMW-E expression in human mammary epithelial cells induces an epithelial t...

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Detalhes bibliográficos
Main Authors: Duong, MyLinh T., Akli, Said, Macalou, Sira, Biernacka, Anna, Debeb, Bisrat G., Yi, Min, Hunt, Kelly K., Keyomarsi, Khandan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773499/
https://ncbi.nlm.nih.gov/pubmed/23955388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0013
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