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Hbo1 is a cyclin E/CDK2 substrate that enriches for breast cancer stem-like cells
Expression of cyclin E proteolytic cleavage products, low molecular weight cyclin E (LMW-E), is associated with poor clinical outcome in breast cancer patients and enhances tumorigenecity in mouse models. Here, we report that LMW-E expression in human mammary epithelial cells induces an epithelial t...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773499/ https://ncbi.nlm.nih.gov/pubmed/23955388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0013 |
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