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Modulation of T Lymphocyte Replicative Senescence via TNF-α Inhibition: Role of Caspase-3()
Expanded populations of CD8(+) T lymphocytes lacking CD28 expression are associated with a variety of deleterious clinical outcomes, including early mortality in the elderly, more rapid progression to AIDS, cardiovascular disease, and enhanced tumor cell growth. In cell culture, irreversible loss of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773494/ https://ncbi.nlm.nih.gov/pubmed/19299722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803449 |
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