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The Nrf2/SKN-1-dependent Glutathione S-transferase π Homologue GST-1 Inhibits Dopamine Neuron Degeneration in a Caenorhabditis elegans Model of Manganism
Exposure to high levels of manganese (Mn) results in a neurological condition termed manganism, which is characterized by oxidative stress, abnormal dopamine (DA) signaling, and cell death. Epidemiological evidence suggests correlations with occupational exposure to Mn and the development of the mov...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773487/ https://ncbi.nlm.nih.gov/pubmed/23721876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2013.05.014 |
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