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Virulence and Pathogenesis of Yellow Fever Virus Serially Passaged in Cell Culture

Viscerotropic virulence of the Asibi strain of yellow fever virus (YFV) for monkeys has been known to be lost after serial passage in HeLa cell monolayers. This phenomenon was investigated in several other mammalian and insect tissue cell lines. Assay in monkeys of original seed virus and of virus a...

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Detalles Bibliográficos
Main Authors: Converse, John L., Kovatch, Robert M., Pulliam, James D., Nagle, Stanley C., Snyder, Ernest M.
Formato: Artigo
Idioma:Inglês
Publicado: 1971
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC377342/
https://ncbi.nlm.nih.gov/pubmed/4998347
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